The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 52  |  Issue : 4  |  Page : 258--263

Polysomnography and antidiuretic hormone secretion pattern in children with primary nocturnal enuresis


Hanan M Hamed1, Amany M Abd Al-Aziz1, Ayat A Motawie1, Amany A. A. Fatouh1, Mona A. M. Awad2, Lamia Afifi3 
1 Department of Pediatric, National Research Centre, Cairo, Egypt
2 Department of Clinical Pathology, National Research Centre, Cairo, Egypt
3 Department of Clinical Neurophysiology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt

Correspondence Address:
Hanan M Hamed
Department of Pediatric, National Research Centre, El-Buhouth Str., Dokki, 12311 Cairo
Egypt

Background Nocturnal enuresis (NE) is one of the most common pediatric sleep-related problems. Data on sleep patterns in children with NE are conflicting. Objective We aimed at studying the sleep architecture, associated breathing problems, and its relation to antidiuretic hormone (ADH) in children with primary NE. Patients and methods This study included 31 children aged 6-18 years with primary monosymptomatic NE and 16 healthy matched controls. They were subjected to a single overnight polysomnography and assessment of ADH levels at 9-11 a.m. and 9-11 p.m. Results Enuretic children had significantly prolonged sleep latency and higher stage N1 percentage, less total sleep time, lower sleep efficiency, and lower rapid eye movement sleep percentage compared with the control group. Ten (32.2%) NE children had nocturnal arrhythmia, whereas six (19.35%) had a respiratory distress index more than 5. Reversed ADH secretion pattern was present in 82% of the NE children. Children with reversed ADH secretion had lower stage N1 and respiratory distress index, and higher sleep efficiency, compared with NE children with normal ADH rhythm. Conclusion Primary NE is associated with disturbed sleep architecture. NE could be a presenting symptom for hidden sleep disordered breathing. The association of NE with cardiac arrhythmia is an interesting finding that requires further research. Most NE children have a reversed pattern of ADH secretion.


How to cite this article:
Hamed HM, Abd Al-Aziz AM, Motawie AA, Fatouh AA, Awad MA, Afifi L. Polysomnography and antidiuretic hormone secretion pattern in children with primary nocturnal enuresis.Egypt J Neurol Psychiatry Neurosurg 2015;52:258-263


How to cite this URL:
Hamed HM, Abd Al-Aziz AM, Motawie AA, Fatouh AA, Awad MA, Afifi L. Polysomnography and antidiuretic hormone secretion pattern in children with primary nocturnal enuresis. Egypt J Neurol Psychiatry Neurosurg [serial online] 2015 [cited 2021 Apr 22 ];52:258-263
Available from: http://www.ejnpn.eg.net/article.asp?issn=1110-1083;year=2015;volume=52;issue=4;spage=258;epage=263;aulast=Hamed;type=0