| ORIGINAL ARTICLE |
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| Year : 2016 | Volume
: 53
| Issue : 2 | Page : 107-110 |
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Vitamin D levels in a sample of Egyptian patients with multiple sclerosis
Dina A Zamzam1, Mohamed M Fouad1, Doaa A Elaidy1, Doaa M Abd-Elaziz2, Azza A Abd-Elaziz1
1 Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
2 Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Correspondence Address:
Mohamed M Fouad
MD, Department of Neurology and Psychiatry, Ain Shams University, Cairo
Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1110-1083.183437
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Background
Environmental factors such as vitamin D deficiency have been linked to the etiology of multiple sclerosis (MS) through interaction with genetic factors. Researches must be carried out to answer the question whether the relationship between vitamin D and MS is consistent and reproducible.
Objective
The aim of the present study was to assess the level of vitamin D in Egyptian MS patients.
Subjects and methods
In total, 111 patients with MS and 33 normal subjects were included in this study. Vitamin D level was estimated for each participant using the enzyme linked immunosorbent assay technique.
Results
Vitamin D levels were significantly lower among MS patients (ranging from 5 to 75 ng/ml with a mean ± SD of 26.4 ± 18.5) when compared with controls [ranging from 25 to 80 ng/ml with a mean of 51.2 ± 19.6 (P < 0.001)]. High expanded disability status scale scores were found to be related to low vitamin D levels.
Conclusion
Patients with MS tended to have lower vitamin D levels, and those with higher (expanded disability status scale) scores were more likely to have lower levels of vitamin D. |
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