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ORIGINAL ARTICLE
Year : 2016  |  Volume : 53  |  Issue : 1  |  Page : 23-27

Estimated glomerular filtration rate in relation to intracerebral hemorrhage in Saudi Arabia


1 Department of Neurology, Ain Shams University, Cairo, Egypt; Department of Neurology, King Abdulaziz Hospital, Mecca, Kingdom of Saudi Arabia
2 Department of Clinical Pathology, Ain Shams University, Cairo, Egypt

Correspondence Address:
Magdy A Mostafa
MD, Department of Neurology, King Abdulaziz Hospital, Mecca, Kingdom of Saudi Arabia

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-1083.176341

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Background Renal dysfunction has been implicated as a risk factor for adverse outcomes after numerous cardiovascular events including stroke. However, most of the stroke studies have focused on ischemic stroke but no enough studies were done on intracerebral hemorrhage. Objective We aimed to determine if renal dysfunction can affect the prognosis after intracerebral hemorrhage especially on the short-term period. Patients and methods A total of 60 patients with the diagnosis of intracerebral hemorrhage for the first time were included in this study. They were 17 female (28%) and 43 males (72%). Their age ranged from 35 to 89 years with median value of 60 years. On admission, all patients were subjected to full clinical assessment and brain computed tomography scan to measure the size of hematoma and calculate the intracerebral hemorrhage score. Glomerular filtration rate was estimated on admission using the Cockcroft-Gault equation. Results There was a significant inverse relation between estimated glomerular filtration rate and hematoma size; also significant negative correlation was found between estimated glomerular filtration rate and intracerebral hemorrhage score (P < 0.05).On the other hand increase in serum creatinine was significantly associated with increase in the hematoma size and increase in the intracerebral hemorrhage score (P < 0.05). Conclusion Renal dysfunction has negative impact on the prognosis of intracerebral hemorrhage.


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